Chapter 6. Tailoring of Bioactive Glasses
| Autor: | Leena Hupa, Kaj Karlsson |
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| Rok vydání: | 2016 |
| Předmět: | |
| DOI: | 10.1039/9781782622017-00136 |
| Popis: | Development of new bioactive glass compositions to a particular application is often based on minor changes in the composition of a glass with well-established properties. The final glass composition should then hopefully meet all the criteria set by the biological behaviour of the bioactive glass device in the implantation site. The composition must also satisfy various criteria of fabrication. Thus, in composition tailoring, several important criteria must be fulfilled. This chapter discusses various principles and possibilities of tailoring bioactive glass compositions from materials research and chemical engineering points of view. The goal is to explain the possibilities offered by various property–composition relations to tailor and choose the best composition for a specific application. Tailoring can greatly reduce the number of in vitro and especially in vivo tests. Choice of glasses for emerging future applications in hard and soft tissue engineering requires a multidisciplinary understanding of both the properties of the glass during manufacture and the performance of the final bioactive glass device over the time needed for tissue regeneration or healing. |
| Databáze: | OpenAIRE |
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