Intramolecular hydrogen bonds in the phenylazomethine biomolecules

Autor:	V. L. Sorokin, G. A. Ksendzova, Oleg I. Shadyro, M. V. Belkov, I. V. Skornyakov, G. B. Tolstorozhev
Rok vydání:	2014
Předmět:	Ftir spectra chemistry.chemical_classification Crystallography Phenylazomethine Chemistry Hydrogen bond Biomolecule Intramolecular force Molecule Atomic and Molecular Physics and Optics Electronic Optical and Magnetic Materials
Zdroj:	Optics and Spectroscopy. 117:44-48
ISSN:	1562-6911 0030-400X
Popis:	The FTIR spectra of the solutions of biologically active molecules (screened phenylazomethines) in CCl4 are studied. The role of the OH- and N=C groups in the formation of the intramolecular H bonds is analyzed. The analysis of the FTIR spectra shows that three types of H bonds (O-H…O-H, O-H…N=C, and O-H…O-H…N=C) are possible in the molecules under study. A correlation of the H-bond formation in the phenylazomethine molecules and the antivirus properties of such molecules is revealed. The antivirus activity is observed for molecules that exhibit intramolecular O-H…O-H…N=C bonds in the absence of free hydroxyls. The antivirus activity decreases when the molecule contains additional OH groups that are not involved in H bonds.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6951f19bae040f61ceacffde4816b8de https://doi.org/10.1134/s0030400x14070236 Zobrazit plný text záznamu Plný text ve formátu PDF