PHYSIOLOGICAL AND BIOCHEMI-CAL ASPECTS OF CORRECTION OF URATE LITHIASIS IN CHICKENS IN EARLY ONTOGENESIS WITH THE USE OF CERTAIN ANTIOXIDANTS

Autor: O. V. Agureeva, Biotechnology-MBA named after K. I. Scriabin, T. O. Azarnova, V. I. Maximov, Biotechnology – Mba named after K. I. Scriabin
Rok vydání: 2021
Předmět:
Zdroj: International bulletin of Veterinary Medicine. 2:112-121
ISSN: 2072-2419
DOI: 10.17238/issn2072-2419.2021.2.112
Popis: At present, in a number of poultry farms, urate lithiasis (uric acid diathesis) is a frequent cause of the death of young animals, the development of which is stimulated by the stresses accompanying industrial incubation, as well as the use of low-quality eggs, which leads to abnormalities in the development of the embryo, including its excretory system, causing a delay of uric acid in the body. This phenomenon is often aggravated by acidosis and a violation of the formation and functionality of thermoregulatory systems, which entails the production of nonviable young animals. The paper considers a method for preventing these negative phenomena through the transovarial use of a composition of optimal concentrations of antioxidants – sodium thioctate and citric acid. According to the results of the studies, it was revealed that the presented composition has a positive effect on the prevention of uric acid diathesis, which was expressed in a decrease in the intensity of lipoperoxidation, against the background of an increase in AOA in experimental chickens by 25,4%. This phenomenon was reflected in the intensity of the central metabolic processes, namely carbohydrate-energy and protein metabolism, which was reflected in the optimization of thermoregulation of experimental chickens. The combination of the above phenomena resulted in the absence of cases of uric acid diathesis in experimental chickens, which was a consequence of the absence of acidosis in experimental chickens (reserve blood alkalinity was 10,8% higher in experimental chickens relative to the control), which is a central aspect in the absence of this pathology. Thus, it can be argued that the composition of BAS presented by us actively levels free radical processes, which expresses the stimulation of the optimization of central metabolic processes and leads to the production of more highly viable young animals.
Databáze: OpenAIRE