Recent Advances in the Biology and Chemistry of Vitamin D

Autor:	G. H. Rasmusson, H. Jones
Rok vydání:	1980
Předmět:	Vitamin Chemistry Active principle chemistry.chemical_element Rickets Calcium medicine.disease Bone resorption chemistry.chemical_compound medicine Vitamin D and neurology Ultraviolet light Food science Hydroxy apatite
Zdroj:	Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products ISBN: 9783709185537
DOI:	10.1007/978-3-7091-8551-3_2
Popis:	The D-vitamins are a group of fat soluble materials with high antirachitic activity. Rickets is a disease of infancy caused by faulty calcium hydroxy apatite deposition in the growing bone. It was Palm (140) in 1890 who found that the disease responded favorably to irradiation of patient’s food or skin by sunlight or ultraviolet light. Mellanby (113) in 1919 first reported the presence of an antirachitic factor in cod-liver oil. This discovery encouraged research on the isolation of the active principle in fish-liver oil, but the low natural concentration of the vitamin made isolation very difficult.
Databáze:	OpenAIRE
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