THE RESEARCH OF ENDOTHELIO- AND CARDIOPROTECTIVE EFFECTS OF LAMOTRIGINE IN EXPERIMENTAL ENDOTHELIAL DYSFUNCTION

Autor: M V Pokrovskiy, T G Pokrovskaya, E V Luchkina, I N Ershov
Rok vydání: 2009
Předmět:
Zdroj: I.P. Pavlov Russian Medical Biological Herald. 17:58-62
ISSN: 2500-2546
0204-3475
DOI: 10.17816/pavlovj2009258-62
Popis: In laboratory animals in nitric oxide deficiency modelling introduction of NO-syntase non-selective inhibitor of L-NAME endothelio- and cardio tropical effects of lamotrigine and valproic acid investigated. Coefficients of endothelial dysfunction, myocardial loading tests are used. Endothelio- and cardioprotective effects of lamotrigine and endothelioprotective effects of valproic acid are revealed.
Databáze: OpenAIRE