| Popis: |
Cadmium (Cd) is an important food contaminant that has a long half-life and high toxicity. Although cereals are among the foods that contribute most to dietary Cd exposure, some cereal constituents, especially those associated with bran, can decrease Cd bioavailability. This chapter focuses on the interaction between dietary Cd and wheat bran. To understand the mechanisms involved in the interaction between bran constituents and dietary minerals, we first review the effects of dietary fiber, phytates, and protein on metal bioavailability. We then discuss possible sources of Cd exposure as well as the toxicological aspects of dietary exposure to Cd. Finally, we review the specific interaction between wheat bran and Cd exposure, including the risk of wheat bran contamination with Cd and information from in vitro and in vivo studies regarding the constituents of wheat that may bind Cd and reduce its gastrointestinal absorption and accumulation. |
