| Autor: |
Ogba Grace Oreva, Chris-Ozokor LiLian Ebeye, Igben Vincent-Junior Onoriode, Enaohwo Taniyowho Mamerhi, Ahama Endurance Efe, Lucky Omamuzo Ogagayere, Okoro Ogheneyebrorue Godswill, Udi Onoriode Andrew |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Asian Journal of Medicine and Health. :1-7 |
| ISSN: |
2456-8414 |
| DOI: |
10.9734/ajmah/2022/v20i12763 |
| Popis: |
Objective: Epidemiologic studies and randomized clinical trials demonstrate that type 2 diabetes can be substantially avoided by making dietary and lifestyle changes rather than relying heavily on medications. This study evaluates the ameliorating effect(s) of Telfairia occidentalis seed administration on the histology of the Hypothalamus and testosterone level in normal and Alloxan-induced diabetes in Wistar rats. Methods: Twenty male Wistar rats, weighing between 120-180 g, were divided into five groups of 4 rats each. Groups 1 and 2 representing Normal Control (NC) and Diabetic Control (DC) received only feed and water. Group 3 normal rats received 300 mg/kg Telfairia occidentalis seed extract; groups 4 and 5 received 50 mg/kg of Metformin and 300 mg/kg of Telfairia occidentalis seed extract respectively. Results: The result revealed that the administration of Telfairia occidentalis seed extract moderately increased the body weight (16.76±1.75%) significantly at (P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
