Serum lipid profiles and post-stroke depression in acute ischemic stroke patients
| Autor: | Ya-Ying Zeng, Wen-Jie Tang, Xinjie Tu, Xiaoqian Luan, Huiping Shen, Jincai He |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Apolipoprotein B biology business.industry medicine.disease Gastroenterology 030227 psychiatry 03 medical and health sciences 0302 clinical medicine Quartile Internal medicine Hamd medicine biology.protein Post-stroke depression lipids (amino acids peptides and proteins) Apolipoprotein A1 business Complication Stroke 030217 neurology & neurosurgery Depression (differential diagnoses) |
| Zdroj: | Neuropsychiatric Disease and Treatment. 15:1573-1583 |
| ISSN: | 1178-2021 |
| DOI: | 10.2147/ndt.s204791 |
| Popis: | Purpose: Post-stroke depression (PSD) is a psychiatric complication after stroke that leads to poorer stroke outcomes. Recent observational studies have indicated that lipid profiles were associated with a higher risk of stroke and depression. This study aims to further explore the possible relationship between serum lipid profiles and the development of PSD. Methods: A total of 373 acute ischemic stroke patients were examined. Serum lipid profiles including high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), total cholesterol (TC), apolipoprotein A1 (Apo A1) and apolipoprotein B (Apo B) were measured within 24 hrs of admission. Depression symptoms were assessed by the 17-item Hamilton Depression Scale (HAMD-17) at the one-month follow-up, and HAMD scores ≥7 indicated a diagnosis of PSD. Results: A total of 114 patients were diagnosed with PSD at the one-month follow-up, for a percentage of 30.6%. There were significant differences in HDL-C levels (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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