An Unusual Non-Radical Phenolic Coupling

Autor:	Del Whybrow, W. Russell Bowman, Natalie V. Bell, Andrew Timothy Turner, Paul Frederick Coe
Rok vydání:	1997
Předmět:	Coupling (electronics) Chemistry Yield (chemistry) Organic Chemistry Drug Discovery Liberation Organic chemistry Ethyl ester Biochemistry
Zdroj:	Tetrahedron Letters. 38:2581-2584
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(97)00407-3
Popis:	4-Substituted-2,6-diiodophenols undergo non-radical ortho-ortho phenolic coupling by an S N 2 mechanism with liberation of I 2 to yield the corresponding biphenyls. In particular, the ethyl ester of N- acetyl-3,5-diiodotyrosine gives good yields of the corresponding dityrosine analogue 2 under mild conditions . © 1997 Published by Elsevier Science Ltd.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::68db58d77dc24e63746f4a8f92a5f578 https://doi.org/10.1016/s0040-4039(97)00407-3 Zobrazit plný text záznamu Full Text from ScienceDirect