| Autor: |
Ren, Dongren, Shaheen, Nicholas J., Zheng, Gaolin, Chen, Xiaoxin, Bream, Susan, Tevebaugh, Whitney |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
|
| DOI: |
10.17615/vg3f-te16 |
| Popis: |
Barrett’s esophagus (BE), the premalignant lesion of esophageal adenocarcinoma, is believed to develop as a result of chronic gastroesophageal reflux disease (GERD). Approximately 10% of subjects with GERD progress to BE. Genetic, epigenetic and other risk factors may contribute to this inter-individual variability. Caudal type homeobox 1 (Cdx1) and Caudal type homeobox 2 (Cdx2) play important regulatory roles in the development of human BE. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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