Histological comparison between predictive value of preoperative 3‐T multiparametric MRI and 68 Ga‐PSMA PET/CT scan for pathological outcomes at radical prostatectomy and pelvic lymph node dissection for prostate cancer
| Autor: | R. Parkinson, Brett Delahunt, Lousie McEwan, John Yaxley, Matthew J. Roberts, Hema Samaratunga, Geoff Coughlin, Anthony Franklin, Boon Kua, David Wong, Sheliyan Raveenthiran, Nicholas Brown, Troy Gianduzzo, Lars Egevad, William Yaxley |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry Prostatectomy Urology medicine.medical_treatment 030232 urology & nephrology medicine.disease Metastasis 03 medical and health sciences Dissection Prostate cancer 0302 clinical medicine medicine.anatomical_structure Positron emission tomography 030220 oncology & carcinogenesis Medicine Radiology business Pathological Lymph node Multiparametric Magnetic Resonance Imaging |
| Zdroj: | BJU International. 127:71-79 |
| ISSN: | 1464-410X 1464-4096 |
| DOI: | 10.1111/bju.15134 |
| Popis: | Objective To evaluate the ability of preoperative multiparametric magnetic resonance imaging (mpMRI) and a gallium-68 prostate-specific membrane antigen positron emission tomography/computed tomography (Ga-68-PSMA PET/CT) scan to predict pathological outcomes and also identify a group of men with a 30% risk of microscopic LNM despite a negative preoperative(68)Ga-PSMA PET/CT and this high-risk group would appear suitable for an extended PLND at the time of a radical prostatectomy. |
| Databáze: | OpenAIRE |
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