Molybdenum-mediated synthesis of quinazolin-4(3H)-ones via cyclocarbonylation using microwave irradiation

Autor:	Bryan Roberts, Nicola J. Webb, Catherine Barber, David J. Liptrot, Robert Dods, Tim Luker, Barrie Martin, Michael J. Stocks
Rok vydání:	2011
Předmět:	chemistry.chemical_compound chemistry Molybdenum Organic Chemistry Drug Discovery Microwave irradiation chemistry.chemical_element Photochemistry Biochemistry Catalysis Palladium Carbon monoxide
Zdroj:	Tetrahedron Letters. 52:3793-3796
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2011.05.052
Popis:	A new, efficient and practical synthesis of quinazolin-4(3H)-ones is reported via molybdenum-mediated cyclocarbonylation using microwave irradiation. These methods allow access to a wide range of quinazolin-4(3H)-ones in reasonable yields without the need for gaseous carbon monoxide and palladium catalysts. A range of reactions illustrating the wide scope of this chemistry was carried out and all proceeded in reasonable yields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::68a3c7bd70b3c6cfc328c320f9be01a7 https://doi.org/10.1016/j.tetlet.2011.05.052 Zobrazit plný text záznamu Full Text from ScienceDirect