Ca2+ sensitivity of skinned ventricular cardiac muscle and expression of cardiac myosin heavy chain isoforms in hibernating versus active frogs
| Autor: | Mukhallad A. Mohammad, Nayef S. Gharaibeh, Mohammad Alqudah, Ramzi Al-Horani, Said Y. Khatib |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Gene isoform
Hibernation medicine.medical_specialty Myofilament 040301 veterinary sciences Cardiac muscle chemistry.chemical_element 04 agricultural and veterinary sciences 030204 cardiovascular system & hematology Hypothermia Calcium Biology Pathology and Forensic Medicine 0403 veterinary science 03 medical and health sciences 0302 clinical medicine Endocrinology medicine.anatomical_structure chemistry Internal medicine Myosin medicine Anatomy medicine.symptom Polyacrylamide gel electrophoresis |
| Zdroj: | Comparative Clinical Pathology. 26:799-804 |
| ISSN: | 1618-565X 1618-5641 |
| DOI: | 10.1007/s00580-017-2449-8 |
| Popis: | Hibernation is a biological phenomenon enabling animals to endure hypothermia. This study was designed to find the changes in myosin heavy chain (MHC) isoforms and their relationship to calcium sensitivity in frog ventricular muscle during hibernation. MHC profile was determined by SDS-4% polyacrylamide gel electrophoresis in active and hibernating frogs for different intervals of time (10, 20, 30, and 60 days). Calcium sensitivity of Triton-skinned ventricular muscle fiber bundles was determined. Compared with active and hibernated frogs for 10 and 20 days, hibernated frogs for 30 and 60 days expressed significant amount (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink