Serum Coenzyme Q10 Levels and Oxidative Status in Patients with Fibromyalgia Syndrome
| Autor: | Pelin Oktayoglu, İbrahim Batmaz, Serda Em, Kemal Nas, Seval Karatoprak, Demet Uçar, Hatice Yüksel, Mehtap Bozkurt, Mehmet Caglayan, Mustafa Akif Sariyildiz |
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| Rok vydání: | 2014 |
| Předmět: |
Coenzyme Q10
medicine.medical_specialty medicine.diagnostic_test business.industry Oxidative phosphorylation Gastroenterology chemistry.chemical_compound Antioxidant capacity Fibromyalgia syndrome Endocrinology Rheumatology chemistry Erythrocyte sedimentation rate Internal medicine medicine In patient Symptom onset business Body mass index |
| Zdroj: | Journal of Musculoskeletal Pain. 22:27-32 |
| ISSN: | 1540-7012 1058-2452 |
| Popis: | Objectives: The aim of this study was to determine the relationship between serum coenzyme Q10 [CoQ10] levels and symptoms of fatigue associated with fibromyalgia syndrome [FMS].Methods: Patients diagnosed with primary FMS and domographically matching healthy normal controls [HNCs] were sought to participate in the study. The total antioxidant status, total oxidative status, and CoQ10 levels were measured in blood samples from the patients and the controls.Results: A total of 40 patients with FMS and 30 HNCs were recruited. There were no statistically significant differences between the two groups in regard to C-reactive protein, mean erythrocyte sedimentation rate, mean age, and mean body mass index [p > 0.05]. The mean time from symptom onset to diagnosis for the FMS patients was 2.88 years, and the average number of tender points was 14. The serum CoQ10 levels were significantly lower in the FMS patients compared with the HNC group [p = 0.000]. The serum total oxidative status and oxidative str... |
| Databáze: | OpenAIRE |
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