A biomimetic synthesis of coelenterazine analogs

Autor: Jacqueline Marchand-Brynaert, Gilles Olive, Ingrid Devillers, Axelle Arrault
Rok vydání: 2002
Předmět:
Zdroj: Tetrahedron Letters. 43:3161-3164
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(02)00462-8
Popis: N-(Trifluoroacetyl)dehydrodipeptides 2-3 were coupled to aminomethylene dimethylacetal derivatives 4 5. The resulting pseudo-tripeptides 6 were stepwise deprotected (carbonyl function (7) then amine function) and in situ cyclized into imidazolopyrazines 1. (C) 2002 Elsevier Science Ltd. All rights reserved.
Databáze: OpenAIRE