Autor:	M. L. F. Wada, Arnaldo R. Santos, Samuel Hilsdorf Barbanti, Sônia Maria Malmonge, Christiane Bertachini Lombello, E. A. R. Duek
Rok vydání:	2002
Předmět:	Morphology (linguistics) Materials science Biomedical Engineering Biophysics Substrate (chemistry) Bioengineering Adhesion Methacrylate Biomaterials Membrane Chemical engineering Polymer chemistry Self-healing hydrogels Adhesive Cell adhesion
Zdroj:	Journal of Materials Science: Materials in Medicine. 13:867-874
ISSN:	0957-4530
DOI:	10.1023/a:1016552413295
Popis:	Cell adhesion is influenced by the physical and chemical characteristics of the materials used as substrate for cell culturing. In this work, we evaluated the influence of the morphological and chemical characteristics of different polymeric substrates on the adhesion and morphology of fibroblastic cells. Cell growth on poly (L-lactic acid) [PLLA] membranes and poly(2-hydroxy ethyl methacrylate) [polyHEMA], poly(2-hydroxy ethyl methacrylate)-cellulose acetate [polyHEMA-CA] and poly(2-hydroxy ethyl methacrylate)-poly(methyl methacrylate-co-acrylic acid) [polyHEMA-poly(MMA-co-AA)] hydrogels of different densities and pore diameters was examined. Cells adhered preferentially to more negativaly charged substrates, with polyHEMA hydrogels being more adhesive than the other substractes. The pores present in PLLA membranes did not interfere with adhesion, but the cells showed a distinctive morphology on each membrane.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6868b6c956fc0deb8cdc567e629f3e6b https://doi.org/10.1023/a:1016552413295 Zobrazit plný text záznamu Full text from SpringerLink