THE WARBURG EFFECT IN THE HEART: INCREASED GLUCOSE METABOLISM DRIVES CARDIOMYOCYTE HYPERTROPHY IN RESPONSE TO ADRENERGIC STIMULATION
| Autor: | Heinrich Taegtmeyer, William P. Dillon, Giovanni Davogustto, Hernan Vasquez, Rebecca Salazar |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
musculoskeletal diseases
medicine.medical_specialty business.industry Cardiomyocyte hypertrophy Human heart 030204 cardiovascular system & hematology Carbohydrate metabolism Structural remodeling Warburg effect 03 medical and health sciences 0302 clinical medicine Endocrinology Adrenergic stimulation 030220 oncology & carcinogenesis Internal medicine Cancer cell Medicine Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of the American College of Cardiology. 71:A802 |
| ISSN: | 0735-1097 |
| Popis: | The Warburg effect in cancer cells entails enhanced lactate production from glucose in the presence of oxygen. We have recently discovered footprints of the Warburg effect in the failing human heart and that metabolic remodeling precedes structural remodeling. Our aim was to test the hypothesis that |
| Databáze: | OpenAIRE |
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