Antioxidant, Antiinflammatory, and Antifibrotic Properties of Quercetin in the Liver
| Autor: | Erika Hernández-Aquino, Pablo Muriel, E.E. Vargas-Pozada, L.F. Vázquez-Flores, Sael Casas-Grajales |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
chemistry.chemical_classification Antioxidant medicine.drug_class medicine.medical_treatment Flavonoid Pharmacology Anti-inflammatory 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology 0302 clinical medicine chemistry Pharmaceutical technology 030220 oncology & carcinogenesis medicine Quercetin |
| Popis: | Quercetin (Q) is a ubiquitous flavonoid founded in several natural sources, mainly in skin apples and red onions. Q possesses potent antioxidant properties, as well as metal-chelating property, sufficient reasons for years worthy of investigation. Experimental evidence shows that Q possesses anti-inflammatory and antifibrotic capacities, which together are beneficial for the treatment of liver diseases. This chapter will explain how Q exerts its effect on liver diseases and the relevant aspects of its chemistry and pharmacokinetic and pharmaceutical technologies. Nevertheless, toxicological effects of Q were also reported; for this reason more studies are necessary to determine the best conditions for the use of Q for the treatment of liver diseases. |
| Databáze: | OpenAIRE |
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