Sterically hindered nitrogen inversion in five-membered cyclic hydrazines

Autor:	Ivan I. Chervin, S. V. Usachev, Yurii A. Strelenko, Pavel A. Belyakov, Grigorii A. Nikiforov, Remir G. Kostyanovsky
Rok vydání:	2002
Předmět:	Steric effects Pyrazolidine chemistry.chemical_compound chemistry Hydrazine Organic chemistry chemistry.chemical_element Pyrazoline General Chemistry Nitrogen inversion Medicinal chemistry Nitrogen
Zdroj:	Mendeleev Communications. 12:189-192
ISSN:	0959-9436
DOI:	10.1070/mc2002v012n05abeh001626
Popis:	We found that (PriNH)2 with MeCHO form only pyrazoline 1 because of the competitive crotonization of the latter followed by reaction with hydrazine; pyrazoline 2, pyrazolidinones 6 and 9, pyrazolidinol 8 and pyrazolidine 7, in which the inversion of nitrogen atoms is hindered by bulky PriN substituents, were prepared for the first time, and the inversion barriers were determined.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::68387179dbb09465fd2a0e2b49798062 https://doi.org/10.1070/mc2002v012n05abeh001626 Zobrazit plný text záznamu Full Text from ScienceDirect