Microbiological reductions of chromen-4-one derivatives

Autor:	Guy Mousset, Marc Payard, Pierre Palvadeau, Genevieve Baziard-Mouysset, Kamal Boubekeur, Pascale Besse, Henri Veschambre
Rok vydání:	1999
Předmět:	Organic Chemistry Substituent Alcohol Bromine atom Ring (chemistry) Catalysis Inorganic Chemistry chemistry.chemical_compound chemistry Phenyl group Organic chemistry Physical and Theoretical Chemistry Enantiomer Enantiomeric excess
Zdroj:	Tetrahedron: Asymmetry. 10:4745-4754
ISSN:	0957-4166
Popis:	From the microbiological reductions of 2-acetyl or 2-benzoylchromen-4-one both enantiomers of the corresponding alcohols were obtained with high enantiomeric excess. The absolute configurations were determined directly by an X-ray structural determination. The results obtained showed that for most of the microorganisms tested, an inversion of the configuration of the alcohol occurred with the change of the substituent (methyl to phenyl group) in position 2, but also with the presence of a bromine atom in position 6 of the aromatic ring, positioned quite far from the prochiral centre.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6826d21c2661fadeddc1d229096b84f7 https://doi.org/10.1016/s0957-4166(99)00558-3 Zobrazit plný text záznamu Full Text from ScienceDirect