Exploring selective recognition between Fe2+, Fe3+ and their implementation in bio-imaging: A combined spectroscopic and theoretical investigation
| Autor: | Niranjan Santra, Soumya Sundar Mati, Palash Das, Shyamal Murmu, Boby Samai, Shaipayan Pal, Dipti Singharoy, Saugata Konar |
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| Rok vydání: | 2019 |
| Předmět: |
inorganic chemicals
Pyrimidine Absorption spectroscopy 010405 organic chemistry Ligand Metal ions in aqueous solution Organic Chemistry 010402 general chemistry Mass spectrometry 01 natural sciences 0104 chemical sciences Analytical Chemistry Ion Inorganic Chemistry chemistry.chemical_compound chemistry Physical chemistry Density functional theory Methylene Spectroscopy |
| Zdroj: | Journal of Molecular Structure. 1184:102-109 |
| ISSN: | 0022-2860 |
| DOI: | 10.1016/j.molstruc.2019.02.020 |
| Popis: | For selective and individual spectroscopic detection of Fe2+ and Fe3+ ions, a pyrimidine based Schiff-base ligand, (2(E)-methyl 2-((6-methyl-2-(methylthio)pyrimidin-4-yl)methylene)hydrazinecarbodithioate, has been used both experimentally and theoretically. Absorption spectra of the ligand was changed in presence of Co2+, Cu2+, Zn2+ and Fe2+ whereas no additional peak is observed in presence of other metal ions including Fe3+. However, it was found that fluorescence quenching of the sensor occurred by both Fe2+ and Fe3+ ions. Nuclear magnetic resonance and mass spectroscopy established that the spectroscopic behavior of the ligand with Fe2+ was due to 1:2 metal-ligand complex formations. In case of Fe3+ similar type of 1:2 metal-ligand complex is formed. Experimental spectral properties have been allied with theoretical findings based on Density Functional Theory (DFT). This sensing application of the ligand was also examined through bio-imaging with human prostate carcinoma (PC-3) cells by Confocal microscope. |
| Databáze: | OpenAIRE |
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