289. Self-monitoring BP in hypertensive pregnancies: The OPTIMUM-BP pilot study

Autor: Richard J McManus, Lucy Mackillop, Sue Ziebland, Katherine L. Tucker, Lucy C Chappell, Louise Pealing, Hannah M. Wilson, Carole Crawford, David Churchill
Rok vydání: 2018
Předmět:
Zdroj: Pregnancy Hypertension. 13:S39
ISSN: 2210-7789
DOI: 10.1016/j.preghy.2018.08.115
Popis: Introduction Hypertension affects around 10% pregnancies and is associated with adverse maternal and fetal outcomes. Clinic blood pressure (BP) is typically used to monitor and titrate antihypertensive medication during pregnancy. In the general adult population, antihypertensive titration using self-monitoring improves BP control. This study aimed to evaluate the feasibility of using a self-monitoring BP intervention in pregnant women with hypertension. Methods Pregnant women with hypertensive disease were enrolled between December 2015 and December 2017 across four UK sites and randomised 2:1 to BP self-monitoring or usual care. Women attended up to 3 antenatal study visits and postnatal follow-up at 6 weeks. Self-monitoring involved daily BP measurements, recording these in a study diary or via mobile-phone based telemonitoring. Results 87 women with chronic hypertension were randomised (56 BP self-monitoring; 31 usual care), representing 65% of those screened and eligible. Eight women declined to join the study (3 for anxiety around self-monitoring and five as they wished to continue self-initiated BP monitoring). Average monthly recruitment ranged from 2.2 to 3.6 participants per site. 98% (n = 85) women completed the study. There were 2 terminations and one early miscarriage. For women who continued monitoring beyond 24 weeks’ gestation [n = 82], 28% (n = 23) developed superimposed pre-eclampsia, 22% (n = 18) of babies were delivered before 37 weeks’ gestation and 11% (n = 9) of birthweights were Conclusions Self-monitoring of hypertension in pregnancy is feasible with good recruitment and retention within the study. The high incidence of maternal and perinatal adverse outcomes may reflect the risks associated with chronic hypertension. These results support a larger trial evaluating the effect of blood pressure self-monitoring on definitive maternal and fetal outcomes.
Databáze: OpenAIRE