Parametric analysis of wax printing technique for fabricating microfluidic paper-based analytic devices (µPAD) for milk adulteration analysis
| Autor: | Liaqat Ali, Mushtaq Khan, Ahmad Nawaz, Ammara Maryam, Syed Husian Imran Jaffery, Muhammad Nabeel Anwar, Muhammad Younas |
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| Rok vydání: | 2019 |
| Předmět: |
Wax
Fabrication Materials science Parametric analysis Filter paper 010401 analytical chemistry Microfluidics 02 engineering and technology Paper based 021001 nanoscience & nanotechnology Condensed Matter Physics 01 natural sciences 0104 chemical sciences Electronic Optical and Magnetic Materials visual_art Line (geometry) Materials Chemistry visual_art.visual_art_medium Composite material 0210 nano-technology Porosity |
| Zdroj: | Microfluidics and Nanofluidics. 23 |
| ISSN: | 1613-4990 1613-4982 |
| DOI: | 10.1007/s10404-019-2208-z |
| Popis: | Accurate prediction of hydrophobic–hydrophilic channel barriers is essential in the fabrication of paper-based microfluidic devices. This research presents a detailed parametric analysis of wax printing technique for fabricating µPADs. Utilizing commonly used Grade 1 filter paper, experimental results show that the wax spreading in the paper porous structure depends on the initially deposited wax line thickness, a threshold melting temperature and melting time. Initial width of the printed line has a linear relationship with the final width of the barrier; however, a less pronounced effect of temperature was observed. Based on the spreading behavior of the molten wax at different parameters, a generalized regression model has been developed and validated experimentally. The developed model accurately predicts wax spreading in Whatman filter paper: a non-uniform distribution of pores and fibers. Finally, tests were carried out for calorimetric detection of commonly used adulterants present in milk samples. |
| Databáze: | OpenAIRE |
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