A relationship between heat load and plasma enzyme concentration
Autor: | A.J. Kielblock, M. Manjoo, F.J. Burger |
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Rok vydání: | 1985 |
Předmět: |
chemistry.chemical_classification
medicine.medical_specialty biology Physiology Chemistry Heatstroke Metabolism Thermoregulation medicine.disease Biochemistry chemistry.chemical_compound Endocrinology Enzyme Plasma enzyme Internal medicine Lactate dehydrogenase medicine biology.protein Creatine kinase Heat load General Agricultural and Biological Sciences Developmental Biology |
Zdroj: | Journal of Thermal Biology. 10:221-225 |
ISSN: | 0306-4565 |
DOI: | 10.1016/0306-4565(85)90044-0 |
Popis: | 1. 1. The sensitivity of serum enzyme levels as indicators of tissue damage is less well established in the prodromal period of heatstroke, especially for sub-lethal stress conditions. 2. 2. Anaesthetized rats were exposed to two different sets of thermal conditions. 3. 3. Plasma levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatine kinase (CK) and lactate dehydrogenase (LD) were assayed in each group upon termination of stress, 6 h post-stress and 24 h post-stress. 4. 4. The tissue “damage” sustained was mild to moderate and completely reversible. 5. 5. The rate of rise in body temperature may constitute an important factor in the ultimate pathology. 6. 6. CK proved to be the most sensitive parameter of tissue “damage”. |
Databáze: | OpenAIRE |
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