Combination of antidepressants and psychological treatments for bulimia nervosa: a systematic review
| Autor: | Phillipa Hay, Josué Bacaltchuk, Jair de Jesus Mari, Maurício Silva de Lima, R. P. Trefiglio, Irismar Reis de Oliveira |
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| Rok vydání: | 2000 |
| Předmět: | |
| Zdroj: | Acta Psychiatrica Scandinavica. 101:256-264 |
| ISSN: | 1600-0447 0001-690X |
| DOI: | 10.1111/j.1600-0447.2000.tb10923.x |
| Popis: | Bacaltchuk J, Trefiglio RP, Oliveira IR, Hay P, Lima MS, Mari JJ. Combination of antidepressants and psychological treatments for bulimia nervosa: a systematic review. Acta Psychiatr Scand 2000: 101: 256–264. © Munksgaard 2000. Background: This review assessed the effect of a combination of antidepressants plus psychological approaches compared to each single treatment for bulimia nervosa. Method: Trials were included in two meta-analyses: single antidepressants versus combination and single psychological approaches versus combination. Methodological quality and homogeneity of results were assessed. Dichotomous outcomes were analyzed by calculating relative risks (RR). Results: Five trials were included in meta-analysis 1 and 7 in meta-analysis 2. Remission rates were 42% for combination versus 23% for antidepressants (RR=1.38; 95% CI = 0.98–1.93; P= 0.06) and 36% for psychological approaches compared to 49% for combination (RR = 1.21; P= 0.03). Drop-out rates were 16%) for psychological approaches and 30% for combination (RR = 0.57; 95% CI = 0.38–0.088: P = 0.11). Conclusion: Efficacy of combined treatments was superior to single approaches. When antidepressants were combined to treatment, acceptability of psychological approaches was significantly reduced. |
| Databáze: | OpenAIRE |
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