| Autor: | Ulrich Brauns, Bernd W. Müller |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Pharmacology
chemistry.chemical_classification Cyclodextrin Precipitation (chemistry) Organic Chemistry Inorganic chemistry Phosphate buffered saline technology industry and agriculture Pharmaceutical Science law.invention carbohydrates (lipids) chemistry.chemical_compound chemistry law Phase (matter) polycyclic compounds Gamma-cyclodextrin Molecular Medicine lipids (amino acids peptides and proteins) Pharmacology (medical) Crystallization Solubility Derivatization Biotechnology |
| Zdroj: | Pharmaceutical Research. :309-310 |
| ISSN: | 0724-8741 |
| DOI: | 10.1023/a:1016301919928 |
| Popis: | The effect of γ-cyclodextrin and its four derivatives on the solubility of progesterone in phosphate buffer pH 7.4 was investigated. γ-Cyclodextrin forms a complex precipitating from solution at low cyclodextrin concentrations. No precipitation of complexes was observed with the γ-cyclodextrin derivatives. This change in phase-solubility behavior is probably due to low crystallization tendencies of the derivatives. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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