Potassium deficiency in rats: Effects on rates of dehydration and electrolyte homeostasis
| Autor: | C.R. Johnson, Ralph P. Francesconi, N. Leva, Roger W. Hubbard |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Hyperthermia
Kidney medicine.medical_specialty Physiology Chemistry Sodium Potassium chemistry.chemical_element medicine.disease Biochemistry Hypokalemia medicine.anatomical_structure Endocrinology Internal medicine medicine Potassium deficiency Dehydration medicine.symptom General Agricultural and Biological Sciences Homeostasis Developmental Biology |
| Zdroj: | Journal of Thermal Biology. 19:129-134 |
| ISSN: | 0306-4565 |
| DOI: | 10.1016/0306-4565(94)90060-4 |
| Popis: | 1. 1.|Three groups of rats were fed a nutritionally complete (C), potassium-deficient (−K), or potassium-supplemented (+K) diet for 28 days followed by passive exposure to a moderate heat stress (Tamb=31.5°C) until a hypohydration level of 8–9% of initial body weight was achieved. 2. 2.|Significant (P < 0.05) hypokalemia was achieved in the −K group and, while final Tre was also increased ifP < 0.05 rmvs C in this group, time to achieve hypohydration and water loss during heat stress were unaffected. 3. 3.|Potassium (K+) levels were decreased and sodium (Na+) concentrations were increased in selected striated muscles of both the +K and −K groups (vs C), but electrolytes in critical tissues (heart, brain, kidney, liver) were unaffected by dietary intake. 4. 4.|The moderate hyperthermia achieved during the dehydration interval elicited minor effects on several indices of heat stress/injury. 5. 5.|The results suggest that the combination of consumption of a K deficient diet for 28 days and exposure to moderate heat stress did not significantly affect dehydration rates or total water loss, but a slightly elevated final Tre was observed in the −K group. |
| Databáze: | OpenAIRE |
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