New in Pathogenesis of Pertes Disease
| Autor: | O. L. Nechvolodova, E. M. Meerson, L. K. Mikhailova, G. I. Nikitina, V. K. Il’ina, V. Ya. Bruskina, S. I. Mitin |
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| Rok vydání: | 1996 |
| Předmět: | |
| Zdroj: | N.N. Priorov Journal of Traumatology and Orthopedics. 3:40-44 |
| ISSN: | 2658-6738 0869-8678 |
| Popis: | The thesises detected do not allow to keep the pathogenesis of PD within the framework of the theory of primary vessels occlusion. In children with PD marked anomalies including the retardation of bone growth, increased rate of signs of general dysplasia of the connective tissue (detected also in near ralations - parents and siblings), changes of nondamaged contralateral head of the femur and spine, disturbance of glycosaminoglycane metabolism, asymmetric retardation of growth of different segments of the limbs. The authors believe that PD is the damage of femur associated with its overloading or another provocing factors that occur on the background of genetically substantiated defect with the damage of bone development. Further infarcts of the head of the femur develop repeatedly and independantly and thus the cupping of PD could be delayed. By the authors opinion PD could not be considerad as femur pathology in a normal child any more but rather as a local manifestation of the general skeleton dysplasia. |
| Databáze: | OpenAIRE |
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