La S-adénosyl-L -homocystéine : 2. Anticonvulsivante
| Autor: | Pierre Fonlupt, Lucien Cronenberger, Maurice Roche, Henri Pacheco, Annie-Claire Andre |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Pharmacology
chemistry.chemical_classification Gamma-aminobutyric acid metabolism Physiology medicine.medical_treatment Strychnine toxicity Stimulation General Medicine Metabolism Neurotransmission nervous system diseases Amino acid chemistry.chemical_compound Anticonvulsant S-Adenosyl-L-homocysteine nervous system Biochemistry chemistry Physiology (medical) medicine cardiovascular diseases |
| Zdroj: | Canadian Journal of Physiology and Pharmacology. 58:493-498 |
| ISSN: | 1205-7541 0008-4212 |
| DOI: | 10.1139/y80-082 |
| Popis: | S-Adenosyl-L-homocysteine (SAH) decreases the epileptiform discharges induced by hippocampic stimulation. SAH reduces the pentetrazol convulsions, does not modify picrotoxine convulsions, and increases strychnine toxicity. These effects are not linked to γ-aminobutyric acid metabolism perturbation or to the concentration of some amino acids known for their action in synaptic transmission. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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