Design and synthesis of new functional compounds related to ferrocene bearing heterocyclic moieties
| Autor: | Abd El-Wareth A. O. Sarhan, Taeko Izumi |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
chemistry.chemical_classification
Organic Chemistry Triazole Pyrazolone Oxadiazole Hydrazone Pyrazole Hydrazide Biochemistry Combinatorial chemistry Inorganic Chemistry chemistry.chemical_compound chemistry Ferrocene Materials Chemistry medicine Organic chemistry Acetylferrocene Physical and Theoretical Chemistry medicine.drug |
| Zdroj: | Journal of Organometallic Chemistry. 675:1-12 |
| ISSN: | 0022-328X |
| DOI: | 10.1016/s0022-328x(03)00216-x |
| Popis: | The synthesis of heterocyclic systems incorporating more than one ferrocene unit was shown to be a facile and convenient route for the synthesis of new ferrocene-heterocycles. Hydrazide 2 was prepared and cyclized to oxadiazole, triazole, and pyrazole using the procedures described in this context with good yields. A pyrazolone derivative could not be obtained and instead a hydrazone derivative 17 was isolated. Hydrazide 2 was condensed with aromatic aldehydes and ferrocene-1,1′-dicarbaldehyde derivatives to give the corresponding hydrazones 11a – c and dihydrazones 12 , 14 and 18 in high yields. Cyclic voltammetry (CV) of the selected ferrocene-heterocycles 8 and 9 was studied comparing with the parent ferrocene and acetylferrocene. The CV of the compound 8 revealed an additional, quasireversible, one-electron oxidation wave at 849 mV, corresponding to the second ferrocene unit connected to the oxadiazole ring through the SCH 2 CO spacer. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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