Bone Mineral Density in Bulgarian Patients with Type 1 Diabetes Mellitus
| Autor: | Marianna Yaneva, Maria M. Orbetzova, Albena D. Botushanova, Nikolay P Botushanov |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Bone mineral
Peak bone mass Deoxypyridinoline medicine.medical_specialty biology business.industry medicine.disease Bone resorption Bone remodeling chemistry.chemical_compound Endocrinology Paget's disease of bone medicine.anatomical_structure chemistry Internal medicine Osteocalcin biology.protein Medicine business Femoral neck |
| Zdroj: | Journal of Osteoporosis and Physical Activity. |
| ISSN: | 2329-9509 |
| DOI: | 10.4172/2329-9509.1000113 |
| Popis: | Aim of the study: To examine the bone mineral density (BMD) in Bulgarian patients with type 1 diabetes mellitus (DM) in comparison to age- sex- and ethnically matched healthy controls and its correlation with bone turnover markers: oteocalcin as a marker of bone formation and deoxypyridinoline cross-laps as bone resorption marker. Materials and methods: 162 patients with type 1 DM (97 females and 65 males) age 29.17 yrs. (20-40) and 200 (100 women and 100 men) age- and sex matched healthy controls were analyzed for BMD and Z-score of lumbar spine and femoral neck by dual X-ray absorptiometry (DXA) using Lunar DPX-A. Plasma levels of osteocalcin and urine levels of deoxypyridinoline cross-laps were determined. Results: BMD in type 1 DM showed statistically significant lower levels for lumbar spine L1-L4- men (1.2114 g/ cm2 ± 0,1587 DM vs. 1.3346 g/ cm2 ± 0,1635 controls, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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