The 1993–94 Généthon human genetic linkage map

Autor:	Jean Morissette, Sophie Marc, Cécile Fizames, Gabor Gyapay, Philippe Millasseau, Alain Vignal, Giorgio Bernardi, Jean Weissenbach, Mark Lathrop, Colette Dib
Rok vydání:	1994
Předmět:	Linkage (software) Genetics Centimorgan Gene mapping Evolutionary biology Genetic linkage Genetic marker Linkage based QTL mapping Microsatellite Biology Complete linkage
Zdroj:	Nature Genetics. 7:246-339
ISSN:	1546-1718 1061-4036
DOI:	10.1038/ng0694supp-246
Popis:	In 1992, we described a second-generation genetic linkage map of the human genome. Using 1,267 new microsatellite markers, we now present a new genetic linkage map containing a total of 2,066 (AC)n short tandem repeats, 60% of which show a heterozygosity of over 0.7. Statistical linkage analysis based on the genotyping of eight large CEPH families placed these markers in the 23 linkage groups. The map includes 1,266 intervals and spans a total distance of 3690 centiMorgans (cM). A total of 1,041 markers could be ordered with odds ratios greater than 1000:1. About 56% of this map is at a distance of 1 cM or less from one of its markers.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::674d0a28a69464b43ffaa213c79d9891 https://doi.org/10.1038/ng0694supp-246 Zobrazit plný text záznamu