Function and morphology of the myocardium in experimental massive pulmonary arterial embolism
Autor: | E. I. Tikhvinskaya, M. S. Tverskaya, A. O. Virganskii, I. Zh. Satylganov, Chumakova Ma, Karpova Vv, V. V. Banin, Rogulenko Rv |
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Rok vydání: | 1991 |
Předmět: |
medicine.medical_specialty
Arterial embolism biology Enzyme histochemistry General Medicine Pharmacology medicine.disease Acetylcholinesterase Cell function General Biochemistry Genetics and Molecular Biology Enzyme assay chemistry.chemical_compound chemistry Internal medicine medicine Splenocyte Cardiology biology.protein Function (biology) |
Zdroj: | Bulletin of Experimental Biology and Medicine. 111:144-147 |
ISSN: | 1573-8221 0007-4888 |
DOI: | 10.1007/bf00842663 |
Popis: | The experiments carried out present the evidence of acetylcholinesterase activity of Wistar rat lymphocytes. It was shown that splenocytes and thymocytes had significantly different levels of the enzyme activity. Peroral administration of phosphor-organic pesticide antio (phormothion) 1/100 and 1/20 LD50 induced the dose-dependent inhibition of splenocyte acetylcholine-esterase activity after 2 months of treatment. It suggests the relation of the immunosuppressive action of pesticide with the interference into the neuromediator mechanisms regulating the lymphoid cell function. |
Databáze: | OpenAIRE |
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