| Autor: |
Arshad H. Khan, Satyam Sangeet |
| Rok vydání: |
2021 |
| Předmět: |
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| DOI: |
10.1101/2021.01.20.427542 |
| Popis: |
Different Indian therapeutic plants have picked up consideration for their restorative properties against neurodevelopmental disorders lately. Bacopa monnieri (B. monnieri), being one of them, finds its utilization significantly in the treatment of cognition and learning. Despite the fact that it possesses such great capacity to treat neurological issues, how precisely it confers its influence is muddled. This study makes a stride towards knowing which phytochemical is significantly associated with granting B. monnieri with therapeutic properties. The docking investigation and the molecular simulation studies proposes that there is no single phytochemical included that imparts B. monnieri a significant medicinal effect. It is really the blend of dominant part of natural phytochemicals present in B. monnieri that bestows the anti-neurological activity to B. monnieri. The ADME studies shows the convergence of properties of phytochemicals of B. monnieri with that of commercially available drugs which suggests that phytochemicals of B. monnieri can used as a potential drug source to treat neurodegenerative and neurodevelopmental disorders. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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