C-reactive protein evolution in obstructive sleep apnoea patients under CPAP therapy
| Autor: | Eleni G. Tzortzaki, Sophia E. Schiza, Izolde Bouloukaki, Panagou Panagiotis, Charalampos Mermigkis, Eleni Vlachaki, Eleftherios M. Kallergis, Nikolaos Tzanakis, Nikolaos M. Siafakas |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Moderate to severe
medicine.medical_specialty biology Poor compliance business.industry Clinical Biochemistry C-reactive protein Respiratory disease Acute-phase protein General Medicine medicine.disease Biochemistry nervous system diseases respiratory tract diseases Surgery Cpap therapy Internal medicine medicine biology.protein Cpap treatment Patient group business |
| Zdroj: | European Journal of Clinical Investigation. 40:968-975 |
| ISSN: | 0014-2972 |
| DOI: | 10.1111/j.1365-2362.2010.02348.x |
| Popis: | Eur J Clin Invest 2010; 40 (11): 968–975 Abstract Background C-reactive protein (CRP) is recognized as a potential factor implicated in atherogenesis and associated cardiovascular morbidity. The aim of our study was to assess the CRP evolution during 1-year follow-up period in obstructive sleep apnoea (OSA) patients under CPAP treatment. Methods Five hundred and twenty-eight patients with newly diagnosed moderate to severe OSA were included. CRP was assessed before CPAP initiation and at the 3rd, 6th and 12th month of the follow-up period. Patients were divided into good and poor CPAP compliance groups. Results A significant reduction in CRP levels was observed after CPAP therapy (0·74 ± 0·62 mg dL−1 vs. 0·31 ± 0·29 mg dL−1, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|