Selective Buchwald–Hartwig arylation of C-amino-1,2,4-triazoles and other coordinating aminoheterocycles enabled by bulky NHC ligands and TPEDO activator

Autor: Alexander V. Astakhov, Andrey Yu. Chernenko, Vadim V. Kutyrev, Gleb S. Ranny, Mikhail E. Minyaev, Victor M. Chernyshev, Valentine P. Ananikov
Rok vydání: 2023
Předmět:
Zdroj: Inorganic Chemistry Frontiers. 10:218-239
ISSN: 2052-1553
Popis: A facile method for selective N-(hetero)arylation of coordinating 3(5)-amino-1,2,4-triazoles under Pd/NHC catalysis using TPEDO as a new efficient Pd(ii) to Pd(0) reductant has been developed.
Databáze: OpenAIRE