A Radical Clock for Reactions of Epoxy Derivatives Induced by Titanocene Chloride

Autor:	Alfonso Fernández-Mateos, R. Rubio Gonzalez, R. Rabanedo Clemente, P. Herrero Teijón
Rok vydání:	2008
Předmět:	chemistry.chemical_classification Nitrile Chemistry Organic Chemistry Epoxy Photochemistry Cleavage (embryo) Medicinal chemistry Chloride Radical cyclization Aldehyde chemistry.chemical_compound Reaction rate constant visual_art Radical clock medicine visual_art.visual_art_medium medicine.drug
Zdroj:	Synlett. 2008:3208-3212
ISSN:	1437-2096 0936-5214
DOI:	10.1055/s-0028-1087410
Popis:	A new radical clock based on pinene derivatives has been designed to measure the radical cyclization rate onto cyano and carbonyl groups and the radical elimination rate of OR and CN. In this system, the known rate constant of cyclobutylcarbinyl radical cleavage is used as the internal clock. At room temperature, the cyclization rate constants for 4-exo and 5-exo processes onto nitrile and aldehyde carbonyl groups are in the order of 107 to 108 s-1. The radical elimination rate constants for CN, OH, OCHO, and OAc are in the order of 105 to 108 s -1. © Georg Thieme Verlag Stuttgart.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::66e8c779275cd57d3ae9e0f854e1e9f2 https://doi.org/10.1055/s-0028-1087410 Zobrazit plný text záznamu