Preclinical QSP Modeling in the Pharmaceutical Industry: An IQ Consortium Survey Examining the Current Landscape
| Autor: | Erica L. Bradshaw-Pierce, Anjaneya Chimalakonda, Bianca M. Liederer, Loveleena Bansal, Edgar Schuck, Alice Tsai, Fan Wu, Marjoleen Nijsen, Mary E. Spilker, Jason R. Chan, Patricia Schroeder, Jerome T. Mettetal, Kha Le, Akihiro Yamada, Brian Topp, Mark Penney, Christine Xu |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
business.industry Management science Computer science Survey result 030226 pharmacology & pharmacy Clinical method Terminology 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Modeling and Simulation Pharmacology (medical) business Drug industry Pharmaceutical industry Systems pharmacology |
| Zdroj: | CPT: Pharmacometrics & Systems Pharmacology. 7:135-146 |
| ISSN: | 2163-8306 |
| DOI: | 10.1002/psp4.12282 |
| Popis: | A cross-industry survey was conducted to assess the landscape of preclinical quantitative systems pharmacology (QSP) modeling within pharmaceutical companies. This article presents the survey results, which provide insights on the current state of preclinical QSP modeling in addition to future opportunities. Our results call attention to the need for an aligned definition and consistent terminology around QSP, yet highlight the broad applicability and benefits preclinical QSP modeling is currently delivering. |
| Databáze: | OpenAIRE |
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