The ratio of glycated albumin to glycated haemoglobin correlates with insulin secretory function
| Autor: | Bong Suk Cha, Ji H. Huh, Byung Wan Lee, Daham Kim, Hyun Chae Lee, Eun S. Kang, Kwang Joon Kim |
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| Rok vydání: | 2012 |
| Předmět: |
Meal
medicine.medical_specialty endocrine system diseases business.industry Endocrinology Diabetes and Metabolism Insulin medicine.medical_treatment Albumin nutritional and metabolic diseases Type 2 diabetes Carbohydrate medicine.disease Endocrinology Insulin resistance Internal medicine medicine business Body mass index Homeostasis |
| Zdroj: | Clinical Endocrinology. 77:679-683 |
| ISSN: | 0300-0664 |
| DOI: | 10.1111/j.1365-2265.2011.04312.x |
| Popis: | JiH.Huh,Byung-WanLee,EunS.Kang,BongS.ChaandHyunC.LeeDivisionofEndocrinologyandMetabolism,DepartmentofInternalMedicine,YonseiUniversityCollegeofMedicine,Seoul,KoreaSummaryObjectiveAlthough glycated haemoglobin (A1c) levels are simi-lar among patients with type 2 diabetes, the glycated albumin(GA)/A1c ratio varies considerably. On the basis of the hypo-thesis that endogenous insulin secretion might be correlated withthe GA/A1c ratio, we investigated whether insulin secretory func-tion or insulin resistance has different effects on the GA/A1cratio in patients with type 2 diabetes using the standardizedliquid meal test.Design Aclinical,retrospectivestudy.Patients and measurementsA total of 758 patients with type 2diabetes ingested a standardized liquid meal (i.e. 500 kcal, 17AE5gfat, 68AE5 g carbohydrate and 17AE5 g protein). The subjects weredivided into two groups: those with GA/A1c ratio |
| Databáze: | OpenAIRE |
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