Effects of Anticoagulants on Thrombolysis Mediated by Tissue Plasminogen Activator in Experimental Thrombosis Model

Autor:	Osamu Takada, Hajime Tsuji, Mitsuru Yoneda, Kazuharu Katoh, Masashi Uno, Yuka Yamada, Katsumi Yamamoto, Kyoichiro Kobayashi, Haruchika Masuda, Masahito Yamagami, Toshiyuki Tamagaki, Keizo Yamada, Masao Nakagawa, Shohei Sawada, Katsumi Nakagawa
Rok vydání:	1993
Předmět:	medicine.medical_specialty business.industry medicine.medical_treatment Hirudin Warfarin Thrombolysis Heparin medicine.disease Thrombosis Tissue plasminogen activator Argatroban Internal medicine medicine Cardiology business medicine.drug Discovery and development of direct thrombin inhibitors
Zdroj:	Current Aspects of Blood Coagulation, Fibrinolysis, and Platelets ISBN: 9784431701231
DOI:	10.1007/978-4-431-68323-0_13
Popis:	Tissue plasminogen activator (t-PA) is being used as thrombolytic therapy for patients with acute myocardial infarction [1], given in combination with anticoagulants such as heparin or warfarin. We compared the effects of the new selective thrombin inhibitors, argatroban and hirudin, with those of heparin, on the thrombolysis mediated by t-PA in an experimental model of thrombosis using the hamster cheek pouch.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::66cdcc5e11c5d57aeca5d5b56bfee507 https://doi.org/10.1007/978-4-431-68323-0_13 Zobrazit plný text záznamu