ChemInform Abstract: Recent Progress in the Use of Pd-Catalyzed C-C Cross-Coupling Reactions in the Synthesis of Pharmaceutical Compounds

Autor:	André F. P. Biajoli, Adriano L. Monteiro, Jones Limberger, Cristiane Storck Schwalm, Thiago S. Claudino
Rok vydání:	2015
Předmět:	Chemistry chemistry.chemical_element Context (language use) General Medicine Combinatorial chemistry Coupling reaction Catalysis Palladium
Zdroj:	ChemInform. 46
ISSN:	0931-7597
DOI:	10.1002/chin.201545274
Popis:	The impressive ability of palladium to assemble C-C bonds between appropriately functionalized substrates has allowed synthetic organic chemists to perform transformations that were previously impossible or only possible using multi-step approaches. In this context, one of the most important and elegant applications of the Pd-catalyzed C-C coupling reactions currently is the synthesis of pharmaceuticals. This review is intended to give a picture of the applications of Pd-catalyzed C-C cross-coupling reactions for the synthesis of drug components or drug candidates regardless of the scale from 2011 through to the end of July, 2014.
Databáze:	OpenAIRE
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