Decarboxylative Aldol-Type Reaction of 2-(Trifluoroacetyl)-1,3-diazoles with Activated Acetic Acids

Autor: Pavel V. Khodakovskiy, Dmitriy M. Volochnyuk, Andrey A. Tolmachev
Rok vydání: 2009
Předmět:
Zdroj: Synthesis. 2009:1099-1104
ISSN: 1437-210X
0039-7881
DOI: 10.1055/s-0028-1087985
Popis: The highly electrophilic ketones 2-(trifluoroacetyl)-1,3-diazoles easily undergo a decarboxylative aldol-type reaction with activated acetic acids to afford heterocyclic trifluoromethyl-substituted alcohols bearing various functionalities.
Databáze: OpenAIRE