Transition metal-free synthesis of α-ketoamides from arylmethyl ketones and alkylphosphoramides

Autor:	Manisha Tripathy, Diptimayee Sahoo, Bhisma K. Patel, Ahalya Behera, Wajid Ali
Rok vydání:	2016
Předmět:	Aqueous solution 010405 organic chemistry General Chemical Engineering Aryl General Chemistry 010402 general chemistry 01 natural sciences Medicinal chemistry 0104 chemical sciences chemistry.chemical_compound Transition metal chemistry Hexamethylphosphoramide Organic chemistry
Zdroj:	RSC Advances. 6:91308-91313
ISSN:	2046-2069
Popis:	A transition metal-free protocol has been developed for the synthesis of α-ketoamides from aryl methyl ketones and alkylphosphoramides in the presence of oxidant, aqueous tert-butyl hydroperoxide (TBHP). A series of aryl methyl ketones having both electron-donating as well as electron-withdrawing groups were successfully employed for the synthesis of their corresponding α-ketoamides using hexamethylphosphoramide and other alkylphosphoramides.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6698cb1670e6401e486aa834c1a47cdd https://doi.org/10.1039/c6ra16118a Zobrazit plný text záznamu