Risk for Contrast Nephropathy in Patients Undergoing Coronarography

Autor: Gaetano La Manna, Leonardo G. Pancaldi, Giorgia Comai, Alessandro Capecchi, Maria Cappuccilli, Elisa Carretta, Sergio Stefoni, Alessandro Lombardi, Luigi Coli, Edlira Maska
Rok vydání: 2010
Předmět:
Zdroj: Artificial Organs. 34:E193-E199
ISSN: 1525-1594
0160-564X
DOI: 10.1111/j.1525-1594.2009.00984.x
Popis: Among the causes of in-hospital acute renal failure, contrast-induced nephropathy ranks third in prevalence. Although it represents a condition of renal impairment with spontaneous recovery, contrast nephropathy should always be considered, because it prolongs hospitalization and it may become a severe complication requiring dialysis. The purposes of this study are: (i) to determine if the application of the most effective contrast-induced nephropathy prevention strategies in the Cardiology Intensive Care Unit can prove to be successful in reducing nephropathy risk; and (ii) to identify which of the involved risk factors persist after the preventive treatment. We examined the patients who had a coronarography at the Bentivoglio hospital from April 2007 to April 2008 who required at least 3 days of permanence in hospital due to the presence of potential risk factors; 136 out of 784 patients were included. Among the selected patients, 21 (15.44%) developed a renal impairment compatible with contrast-induced nephropathy. The risk factors that seemed to display the best correlation with risk of contrast nephropathy were advanced age and an ventricular failure (ejection fraction 70 years) determined a threefold increased risk of contrast nephropathy. Our data suggest that the development of contrast nephropathy following coronarography is associated with worse renal function during hospitalization and at discharge.
Databáze: OpenAIRE