| Autor: |
Zaky F Aref, Mohamed Alemam, Aida A. Abdelmaksoud, Shamardan Es Bazeed |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
SVU-International Journal of Medical Sciences. |
| ISSN: |
2636-3402 |
| DOI: |
10.21608/svuijm.2020.45265.1014 |
| Popis: |
Objective: The object of this study is to evaluate the relation between 25- hydroxy cholecalciferol (vitamin D3) deficiency and allergic rhinitis by detecting level of 25-hydroxy cholecalciferol and Immunoglobulin E serum levels. Methods: This is a case-control study in which we compare two groups; group A included 69 patients diagnosed as allergic rhinitis (AR) and group B included 60 healthy individuals. Serum levels of cholecalciferol and serum levels of immunoglobulin (IgE) were assessed in all participants of both groups of this study. Results: Serum level of 25- hydroxy cholecalciferol in group A (AR patients) was statistically significantly lower (mean ± SD: 14.2±8.04 ng/ml) than serum level of 25-hydroxy cholecalciferol in group B (21.1±8.2ng/ml). Also serum level of IGE in group A was markedly elevated in comparison to group B (494.4±61.7u/l) vs. (189.9±52.9u/l) with highly statistically significant difference (p-value < 0.001). Conclusion: There is statistically significant relation between 25-hydroxy cholecalciferol deficiency and allergic rhinitis; further studies must be done to assess the effect of Vitamin D3 therapy in allergic rhinitis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
