Total Synthesis ofrac-Silandrin, an Antihepatotoxic Flavanolignan

Autor:	T. S. Toth, Sándor Antus, Agnes Gottsegen, József Szunyog, T. Kovacs, Hildebert Wagner, Eszter Baitz-Gács
Rok vydání:	1993
Předmět:	Lignan chemistry.chemical_compound chemistry Caffeic acid ethyl ester Bicyclic molecule Stereochemistry Organic Chemistry Regioselectivity Total synthesis Organic chemistry Physical and Theoretical Chemistry Coniferyl alcohol
Zdroj:	Liebigs Annalen der Chemie. 1993:105-109
ISSN:	1099-0690 0170-2041
DOI:	10.1002/jlac.199319930119
Popis:	The first synthesis of racemic silandrin (rac-1), which shows significant antihepatotoxic activity, has been accomplished via the key intermediate 9 prepared from the readily available starting materials caffeic acid ethyl ester (4) and coniferyl alcohol (5).
Databáze:	OpenAIRE
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