Chemoenzymatische Synthese von N6-Carbamoyl-D-4-thialysin und N7-Carbamoyl-D-homo-5-thialysin
Autor: | Karlheinz Drauz, Herbert Klenk, Matthias Kottenhahn |
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Rok vydání: | 1992 |
Předmět: | |
Zdroj: | Journal f�r Praktische Chemie/Chemiker-Zeitung. 334:214-218 |
ISSN: | 1521-3897 0941-1216 |
DOI: | 10.1002/prac.19923340303 |
Popis: | Chemoenzymatical Synthesis of N6-Carbamoyl-D-4-thialysine and N7-Carbamoyl-D-homo-5-thialysine The combination of classical chemical and enzymatical methods opens a way to highly functionalized chiral molecules like N6-carbamoyl-D-4-thialysine (5) or N7-carbamoyl-D-homo-5-thialysine (6). The biotransformation of the corresponding hydantoines with Agrobacterium radiobacter is creating the desired D chirality. |
Databáze: | OpenAIRE |
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