Chemoenzymatische Synthese von N6-Carbamoyl-D-4-thialysin und N7-Carbamoyl-D-homo-5-thialysin

Autor: Karlheinz Drauz, Herbert Klenk, Matthias Kottenhahn
Rok vydání: 1992
Předmět:
Zdroj: Journal f�r Praktische Chemie/Chemiker-Zeitung. 334:214-218
ISSN: 1521-3897
0941-1216
DOI: 10.1002/prac.19923340303
Popis: Chemoenzymatical Synthesis of N6-Carbamoyl-D-4-thialysine and N7-Carbamoyl-D-homo-5-thialysine The combination of classical chemical and enzymatical methods opens a way to highly functionalized chiral molecules like N6-carbamoyl-D-4-thialysine (5) or N7-carbamoyl-D-homo-5-thialysine (6). The biotransformation of the corresponding hydantoines with Agrobacterium radiobacter is creating the desired D chirality.
Databáze: OpenAIRE