Percutaneous Gastrostomy in Necrotizing Pancreatitis: Friend or Foe?

Autor: Nicholas J. Zyromski, Glen A. Lehman, Alexandra M. Roch, Rosalie A. Carr, James L. Watkins, Eugene P. Ceppa, Attila Nakeeb, C. Max Schmidt, Michael G. House
Rok vydání: 2019
Předmět:
Zdroj: Journal of Gastrointestinal Surgery. 24:2800-2806
ISSN: 1873-4626
1091-255X
Popis: Enteral nutrition plays a central role in managing necrotizing pancreatitis (NP). Although the nasojejunal (NJ) route is widely used, percutaneous gastrostomy (PEG-J) is an alternative technique that is also applied commonly. We hypothesized that NJ and PEG-J had similar morbidity in the setting of NP. All patients receiving preoperative enteral nutrition before surgical debridement for NP (2005–2015) were segregated into NJ or PEG-J. A total of 242 patients had complete data for analysis (155 men/87 women; median age 54 years; 47% biliary and 16% alcohol-related pancreatitis). NJ was used exclusively in 187 patients (77%); 25 patients (10%) were fed exclusively by PEG-J; the remaining 30 patients (13%) had NJ first, followed by PEG-J. Equal proportions of NJ and PEG-J patients reached enteral feeding goal (67% vs. 68%, p ≈ 1) and increased serum albumin (39% vs. 36%, p = 0.87). No difference was seen in rate of pancreatic necrosis infection (NJ 53% vs. PEG-J 49%, p = 0.64). NJ patients had significantly more complications compared to PEG-J (51%vs.27%,p = 0.0015). However, NJ patients had more grade I/II complication, compared to PEG-J patients, who had more grade III/IV complication (Grade I/II: NJ 51%vs. PEG-J 16%; Grade III/IV NJ 0%vs. PEG-J 11%, p < 0.0001). In necrotizing pancreatitis, NJ and PEG-J both delivered enteral nutrition effectively. Patients with NJ feeding had significantly more complications than those with PEG-J; however, NJ complications were less severe.
Databáze: OpenAIRE
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