Morphological and behavioral alterations induced by endocrine disrupters in amphibian tadpoles

Autor: Katti Pancharatna, Manjunath G. Ghodageri
Rok vydání: 2011
Předmět:
Zdroj: Toxicological & Environmental Chemistry. 93:2012-2021
ISSN: 1029-0486
0277-2248
DOI: 10.1080/02772248.2011.621595
Popis: Developmental toxicity effects of endocrine disrupter chemicals, acephate and cypermethrin were studied in Bufo melanostictus tadpoles. Thirty developing eggs of B. melanostictus were exposed to each concentration (0.01, 0.05, 0.1, 0.5, and 1 µg L−1) of acephate or cypermethrin in the laboratory (temperature: 23 ± 1°C; photoperiod: 11.5–12.5 h). Eggs maintained in conditioned water alone served as controls. After hatching, larvae were fed on boiled spinach until the completion of metamorphosis. In control group, larvae that hatched on 3rd day were heavily pigmented, voracious feeders, and active swimmers; in these tadpoles, hind limb and forelimb-buds emerged on 16th and 24th day and metamorphosis was complete on 32nd day. Eggs exposed to acephate also hatched on 3rd day but larvae exhibited deformities such as, (i) tail distortions, (ii) laterally crooked trunk, (iii) decreased pigmentation, (iv) inactivity, (v) peeling of the skin, and (vi) delay in emergence of limbs and completion of metamorphosis. Cy...
Databáze: OpenAIRE