G402(P)Clinical Profile of Tuberculosis in Pediatric HIV/AIDs
| Autor: | S Shivananda, K. S. Sanjay, M Govindaraju, N Benakappa, GC Bharmappanavara, S Pragalathakumar, GN Sanjeeva, KN Vykuntaraju |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Tuberculosis medicine.diagnostic_test Pediatric hiv business.industry medicine.medical_treatment Immunosuppression Mantoux test medicine.disease Surgery Acquired immunodeficiency syndrome (AIDS) Internal medicine Pediatrics Perinatology and Child Health Vomiting Medicine Sputum medicine.symptom business Wasting |
| Zdroj: | Archives of Disease in Childhood. 99:A167-A168 |
| ISSN: | 1468-2044 0003-9888 |
| DOI: | 10.1136/archdischild-2014-306237.383 |
| Popis: | To study Prevalence and Clinical spectrum of Tuberculosis in Paediatric HIV/AIDS. Methods 320 children with HIV/AIDS enrolled in this study between September 2004 and September 2007. History, Examination, relevant investigations done and classified according to RNTCP, WHO and Immunological stages. SPSS soft ware and t-test used for statistical analysis. Results Prevalence of tuberculosis is 18.12%(58) with Male:Female ratio of 1.22:1 among which unimmunised were 15%. Most common age group was 1–5 years (43.1%), and common presenting symptoms were fever (65.5%), cough (54.5%), FTT in 60%, head ache (20%),vomiting (15%). History of contact was available in 22%. All children weighed Conclusion and recommendations -Tuberculosis is one of commonly prevalent infection in children with HIV with prevalence of 18.12% (49) with Male:Female ratio of 1.22:1 with most common age 1–5 years (43.1%) –Pulmonary tuberculosis was commonest type followed by CNS tuberculosis with disseminated and extrapulmonary tuberculosis being more common with advanced immunosuppression –Fever (65.5%), cough (54.5%), FTT(60%), head ache (20%),vomiting (15%),contact History (22%),unimmunized status (15%) and wasting (90%) are common at presentation. -Relation between Mantoux test positivity and severe immunosuppression was statistically significant. Contact history, Mantoux test and radiological examination with sputum microscopy can be used for diagnosis in resource-limited settings. –Tuberculosis can occur in any CD4 count. Poor outcome were seen in severe immune suppression which was statistically significant. –HIV disease category, severe immunosuppression with associated severe malnutrition at diagnosis were significantly associated with mortality –All HIV positive children should be screened for tuberculosis at time of diagnosis of HIV and annually screened. |
| Databáze: | OpenAIRE |
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